MELANOTAN-1 — Skin & Photoprotection Peptide
Melanin activation • UV defense • Skin tone optimization
Melanotan-1 (also known as Afamelanotide) is a synthetic analog of α-melanocyte-stimulating hormone (α-MSH) — the natural peptide responsible for regulating melanin production, pigmentation, and photoprotection in human skin.
Rather than tanning the skin through UV damage, Melanotan-1 works by stimulating the body’s own melanin pathways, increasing the skin’s ability to darken, defend, and repair itself in response to light exposure.
In research and clinical environments, Melanotan-1 has been shown to support:
• Increased melanin synthesis
• More even pigmentation
• Reduced UV-induced DNA damage
• Lower oxidative stress in skin cells
• Improved skin resilience and tone
Melanotan-1 is distinct from Melanotan-2 in that it produces a slower, more natural-looking pigment increase with significantly fewer systemic side effects — making it the preferred compound in dermatology and photoprotection research.
Why Melanotan-1 is different
Melanotan-1 does not force skin color.
It activates the skin’s natural biological defense system.
By increasing melanin — the body’s built-in UV shield — it allows skin to:
• Tan more evenly
• Resist sunburn
• Reduce oxidative damage
• Maintain healthier pigmentation patterns
• Support long-term skin integrity
This makes Melanotan-1 a leading compound in skin-health, anti-aging, and photoprotection research.
Used in research to study
• UV damage prevention
• Pigmentation disorders
• Skin aging
• Oxidative stress
• DNA repair mechanisms
PHP™ Research Performance Standard
Our Melanotan-1 is supplied as a research-grade lyophilized compound manufactured in GMP-certified facilities and verified for:
✔ Identity
✔ Purity
✔ Potency
✔ Endotoxin levels
Every vial meets the Pure Science. Raw Power. standard.