MELANOTAN-1 — Skin & Photoprotection Peptide

Melanin activation • UV defense • Skin tone optimization

Melanotan-1 (also known as Afamelanotide) is a synthetic analog of α-melanocyte-stimulating hormone (α-MSH) — the natural peptide responsible for regulating melanin production, pigmentation, and photoprotection in human skin.

Rather than tanning the skin through UV damage, Melanotan-1 works by stimulating the body’s own melanin pathways, increasing the skin’s ability to darken, defend, and repair itself in response to light exposure.

In research and clinical environments, Melanotan-1 has been shown to support:

• Increased melanin synthesis • More even pigmentation • Reduced UV-induced DNA damage • Lower oxidative stress in skin cells • Improved skin resilience and tone

Melanotan-1 is distinct from Melanotan-2 in that it produces a slower, more natural-looking pigment increase with significantly fewer systemic side effects — making it the preferred compound in dermatology and photoprotection research.

Why Melanotan-1 is different

Melanotan-1 does not force skin color. It activates the skin’s natural biological defense system.

By increasing melanin — the body’s built-in UV shield — it allows skin to:

• Tan more evenly • Resist sunburn • Reduce oxidative damage • Maintain healthier pigmentation patterns • Support long-term skin integrity

This makes Melanotan-1 a leading compound in skin-health, anti-aging, and photoprotection research.

Used in research to study

• UV damage prevention • Pigmentation disorders • Skin aging • Oxidative stress • DNA repair mechanisms

PHP™ Research Performance Standard

Our Melanotan-1 is supplied as a research-grade lyophilized compound manufactured in GMP-certified facilities and verified for:

✔ Identity ✔ Purity ✔ Potency ✔ Endotoxin levels

Every vial meets the Pure Science. Raw Power. standard.